Study Report on Retrospective Clinical Follow-up of Post Exposure Prophylaxis with Inj. Anti Rabies Vaccine (ARV) or Inj. Anti Rabies Vaccine (ARV) + Inj. Rabies Immunoglobulin (RIG) in Animal Bite Patients Attending at BITID

Abstract

Rabies is a universally fatal and equally preventable zoonotic disease that is prevalent in Bangladesh. Bangladesh Institute of Tropical & Infectious Diseases (BITID) is the national institute for tropical-infectious diseases in the country which is working as a center for rabies control under the Rabies Elimination Program of the Centers for Disease Control and Prevention (CDC). This report is about the cumulative follow-up of patients inflicted with animal bites who had attended the institute during the period of September 2014 to December 2015. The characteristics of animal bites and subsequent clinical outcome of the post-exposure prophylaxis with ARV and/or RIG in the prevention of Rabies was recorded. About 1398 patients were analyzed in two groups, Group A comprised of 886 patients receiving Inj ARV only and Group B included 512 patients who received both of Inj ARV and RIG. Among the analyzed patients, Category lll bites were more prevalent at 54.7%. The total of 84% of the patients who attended for rabies PEP completed the vaccination schedule. Most of the CAT- III patients attended the institute within 2 days of the animal bites. No patients had any adverse effect following vaccination or RIG and none had developed Rabies.